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Lysine isotopologues, compositions comprising the same and methods of synthesis
专利权人:
发明人:
Joel Chandler Bradley,William Wakefield Wood,Salim Barkallah,William James Ryan,Richard Charles Titmas,Mark Donald Schwinden,Janusz Konrad Kozak,Marwan ElMasri,Steven Michael Torkelson
申请号:
US14773284
公开号:
US09840457B2
申请日:
2014.03.12
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention relates to lysine isotopologues of Formulas I and 1-A, as described herein, and processes for synthesizing the same and derivatives and intermediates involved therein. In one aspect, described herein is a chemical compound comprising an isotopically labeled analog, i.e., an isotopologue of a standard or naturally occurring lysine. The lysine isotopologue is synthetically formed to have stable isotopes of elements incorporated at selected positions. As such, the lysine isotopologue has a molecular mass different from the mass of a standard or naturally occurring lysine.
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