Advanced Technologies and Regenerative Medicine; LLC
发明人:
Su, Dongling,Lopez, Julius
申请号：
AU2009236459
公开号：
AU2009236459B2
申请日:
2009.04.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Improved formulations and methods are provided for stabilizing a solution of bone morphogenetic protein. The compositions comprise an acetate buffered solution of GDF-5 and other excipients wherein the solution has a pH of from about 4.2 to about 5.3, thereby providing for a biologically isotonic solution having improved stability of the GDF-5 protein during storage, handling, and use.
