ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE; LLC
发明人:
DONGLING SU,JULIUS LOPEZ
申请号：
BRPI0911048
公开号：
BRPI0911048A2
申请日:
2009.04.08
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
Improved formulations and methods are provided for stabilizing a solution of bone morphogenetic protein. The compositions comprise an acetate buffered solution of GDF-5 and other excipients wherein the solution has a pH of from about 4.2 to about 5.3, thereby providing for a biologically isotonic solution having improved stability of the GDF-5 protein during storage, handling, and use.
