COMPOSITION FOR ALLEVIATING, PREVENTING, OR TREATING SOMNIPATHY OR COMPOSITION FOR SUPPRESSING RESISTANCE TO BENZODIAZEPINE BINDING SITE AGONIST OF GABA-A RECEPTOR OR FOR ALLEVIATING SIDE-EFFECT OF BENZODIAZEPINE BINDING SITE AGONIST OF GABA-A RECEPTOR, EACH COMPOSITION COMPRISING PHLOROGLUCINOL AS EFFECTIVE INGREDIENT
CHO, Sueng Mok,UM, Min Young,YOON, Min Seok,YANG, Hye Jin,LEE, Jae Kwang,JUNG, Jong Hoon
申请号:
WO2018KR05389
公开号:
WO2018208107(A1)
申请日:
2018.05.10
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要:
A pharmaceutical composition for preventing or treating somnipathy or a health function food composition for alleviating somnipathy, each composition comprising phloroglucinol as an effective ingredient, according to the present invention can quickly and reliably induce or maintain sleep. Meanwhile, the composition can prevent a repeated awakening phenomenon without changing a physiological sleep architecture, has no residual sedation, which may particularly give rise to incomplete daytime activities or recognition ability, does not induce resistance after long-term administration, and does not generate a side-effect of conventional benzodiazepine binding side agonist of the GABA-A receptor. In addition, a pharmaceutical composition or a health functional food composition comprising phloroglucinol as an effective ingredient for suppressing resistance to a benzodiazepine binding site agonist of the GABA-A receptor or alleviating a side effect of a benzodiazepine binding site agonist of the GABA-A receptor, acc