INDUSTRY-ACADEMIC COOPERATION FOUNDATION; YONSEI UNIVERSITY
发明人:
CHOI, KANG YELL,최강열,CHA, PU HYEON,차부현
申请号：
KR1020120024525
公开号：
KR1020130103131A
申请日:
2012.03.09
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A pharmaceutical composition containing gallocatechin for preventing and treating bone diseases is provided to complement the weakness of a conventional bone loss inhibitor without side effects because the pharmaceutical composition is derived from a natural product, thereby effectively treating osteoporosis and related diseases thereof.CONSTITUTION: A pharmaceutical composition for preventing and treating bone diseases contains gallocatechin as an active ingredient. Gallocatechin activates Wnt/beta-catechin signal transduction system and promotes osteogenesis by the activation of the Wnt/beta-catechin signal transduction system. The bone disease is osteoporosis. The pharmaceutical composition is used by oral, parenteral, intra-arterial, intradermal, percutaneous, intramuscular, intraperitoneal, intravenous, subcutaneous, and intranasal administration.COPYRIGHT KIPO 2013[Reference numerals] (AA) Control group (BB) Positive control group (5&mug/ml)본 발명은 골질환 예방 및 치료용 약학조성물에 관한 것으로 좀 더 상세하게는 갈로카테킨(Gallocatechin)을 유효성분으로 함유하는 골 질환 예방 및 치료용 약학조성물에 관한 것이다. 본 발명에 의한 조성물은 천연물로부터 유래되어 부작용이 없고, 뼈의 분해 억제가 아닌 형성을 촉진하여 기존의 뼈 분해억제제의 단점을 보완하여 골다공증 및 관련 질병의 치료에 효과적이다.
