A SKIN WHITENING COMPOSITION CONTAINING EXTRACT DERIVED FROM NATURAL RUBBER LATEX SERUM INCLUDING PROTEASE INHIBITOR AND ITS ACTIVE PEPTIDE FRAGMENTS. THE EXTRACTION PROCEDURES INCLUDE ACID AND HEAT TREATMENTS, ULTRAFILTRATION AND SOLVENT FRACTIONATION. THE EXTRACT IS FOUND TO BE EFFECTIVE IN INDUCING DEPIGMENTATION OF MAMMALIAN SKIN. FIGURE 1