The present invention provides a compound of the following formula (I):ring Q represents an optionally substituted monocyclic aryl group、an optionally substituted monocyclic heteroaryl group、an optionally substituted condensed aryl groupring or an optionally substituted condensed heteroaryl group、Y1represents a single bond or －NR6－, etc., ring A represents an optionally substituted non－aromatic heterocyclic diyl group, formula－Y2Z1－ represents a group of the following formula:each of the R7represents a hydrogen atom or an optionally substituted lower alkyl group, etc., each of the R8and R9represent a hydrogen atom or an optionally substituted lower alkyl group, n is an integer of 0~3, Z1represents a single bond, O, S or NR9, ring B represents an optionally substituted aromatic carbon cyclo diyl group, or an optionally substituted aromatic heterocyclo diyl group, Y3represents a single bond, a lower alkylene group that optionally substituted and may mediated with －O－, or an optionally substituted lower alkenylene group, etc., Z2represent COOR3, etc.), or the pharmaceutical acceptable salt thereof or the solvate thereof.本發明為提供如下式(I)：環Q為可被取代之單環芳基、可被取代之單環雜芳基、可被取代之稠合芳基或可被取代之稠合雜芳基，Y1為單鍵或－NR6－等，環A為可被取代之非芳香族雜環二基，式：－Y2Z1－為之基，R7各為氫或可被取代之低烷基等，R8及R9各為氫或可被取代之低烷基，n為0~3之整數，Z1為單鍵、O、S或NR9，環B為可被取代之芳香族碳環二基或可被取代之芳香族雜環二基，Y3為單鍵、可被取代而可有－O－介入之低伸烷基或可被取代之低伸烯基等，Z2為COOR3等)之化合物、其製藥容許鹽或其溶劑合物。
