The system produced a intelligent interface that collects biomedical data to intelligently classify disease(Cancer,Heart disease,Arthritis) information and detect diseases in an earlier stage. Classification is done on the basis of gene classification of various cancers(oral,lung etc.) Soft computing approach will be used.(genetic algorithm+ Naive Bayes+ K-Means clustering + MLP + Simple logistic). The method will identify and recognize the cancer cells with the formulation of gene expressions and soft-computing paradigms in a earlier stage in a efficient way. All the information and outcomes will come under the structure of numerical approach rather than image processing approach.The summation of the all these techniques will produce intelligent clustering & classification of cancer.