Isis del Carmen Torrens Madrazo,Maribel Guerra Vallespi,Milaid Granadillo Rodriguez,Osvaldo Reyes Acosta,Boris Ernesto Acevedo Castro
申请号：
US12671335
公开号：
US08673313B2
申请日:
2008.07.31
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to use of a new cell penetrating peptides (CPP) and in particular to the region 32-51 of protein Limulus antilipopolisacárido (LALF) and its analogous. This invention refers to compositions containing these peptides associated to biomolecules with therapeutics properties. This invention consist of compositions comprise the covalent fusion of biomolecules, between this human papillomavirus antigens (HPV) to these CPP for induce a potent immune cellular responses against HPV and HPV protein antigen-exhibiting cells including HPV-associated tumors. The referred compositions are applicable in the pharmaceutical industry as vaccine for therapeutic use in human.
