IVANJESKU, MARYANNE MAYA,DAUGHERTY, KRISTIN,BOHINC, TATJANA,BUCKLEY, STEPHEN
申请号：
CA3064953
公开号：
CA3064953A1
申请日:
2018.05.25
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
A stabilized composition for the controlled delivery of probiotics includes an aqueous solution of crystalloids and colloids comprised of water insoluble polymers with the ability to de-swell upon electrical charge. The composition further includes a plurality of oil droplets and a base solution. The composition further include a destabilizing solution comprising a solvent, nitrogen, a natural acid sufficient to produce a pH of about 3.0 to about 4.5, and a sufficient amount of a salt to contribute to an osmolality between about 190 mOsm/L and about 900 mOsm/L. The composition further includes a plurality of microencapsulated probiotic beads, wherein the plurality of microencapsulated probiotic beads comprises between about 0.01% to about 20% of the composition by weight.
