THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
LU, Helen, H.,BOUSHELL, Margaret, K.
申请号:
USUS2014/033843
公开号:
WO2014/169236A1
申请日:
2014.04.11
申请国别(地区):
WO
年份:
2014
代理人:
摘要:
Biomimetic hydrogel and selected ceramic interface scaffolds useful in regenerating calcified cartilage and promoting stable and integrative cartilage repair are provided. An aspect of this application relates to scaffolds for promoting calcified cartilage and/or bone fomiation. The scaffolds of this application comprise a biomimetic hydrogel and a ceramic structure or mineral source selected to modulate biosynthesis and mineralization of chondrocytes.Linvention concerne des échafaudages dhydrogel biomimétique et dinterface de céramique sélectionnée, utiles pour régénérer un cartilage calcifié et favoriser une réparation de cartilage stable et entière.