Linda Masat,Mary Haak-Frendscho,Arnold H. Horwitz,Gang Chen,Marina Roell
申请号：
US13739707
公开号：
US09206252B2
申请日:
2013.01.11
申请国别(地区):
US
年份:
2015
代理人:
摘要：
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.
