Linda Masat,Mary Haak-Frendscho,Gang Chen,Arnold Horwitz,Marina Roell
申请号：
US13109680
公开号：
US20120014967A1
申请日:
2011.05.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.
