[the problem to be solved in the present invention]1 new substitution phenylamino 2-dihydroquinoline derivatives of To research synthesis have low alkyl group and import discovery and its salt of the phenyl of ester structure as substituent group and its salt and derivative pharmacological action.[solution] Solving] inThe compound and its salt (1) that general formula indicates can be used for glucocorticoid receptor modulator. R1 indicates hydrogen atom or low alkyl group； R2 indicates hydrogen atom or low alkyl group； R3 and R4 can be identical or different, represents hydrogen atom or low alkyl group； R5 indicates hydrogen atom or low alkyl group； R6 indicates halogen atom, low alkyl group, hydroxyl, lower alkoxy, nitro or cyano； X representatives-c (zero)-, (-) NR8- O ,-S (O) 2- etc.； R7 and/or R8 can be it is identical or different, indicate hydrogen atom, can have substituent group low alkyl group, can have substituent group aryl, can have a substituent group, can have the heterocycle of substituent group, with the lower alkoxy etc. with substituent group； Y represents alkylidene； P represents 0,1,2 or 3.Å studere syntesen av nye 1,2-dihydroquinolinderivater som har substituert fenylkalko-genolavere alkylgruppe og esterintrodusert fenylgruppe som substituenter og et salt derav, og for å finne en farmakologisk virkning til derivatet og et salt derav. Forbindelsene representert ved generell formel (1) og et salt derav er anvendelige for glukokortikoidreseptormodulator. R1 representerer et hydrogenatom eller en lavere alkylgruppe； R2 representerer et hydrogenatom eller en lavere alkylgruppe； R3 og R4 kan være like eller forskjellige og representerer et hydrogenatom eller en lavere alkylgruppe； R5 representerer et hydrogenatom eller en lavere alkylgruppe； R6 representerer et halogenatom, en lavere alkylgruppe, en hydroksygruppe, en lavere alkoksygruppe eller en nitrogruppe； X representerer -C(O)-, -C(0)NR8-, -S(0)2- og lignende； R7 og/eller R8 kan være like eller
