Optical pure quinazoline compounds, particularly compounds of general formula (I), wherein R1 and Y are defined as in the specification, preparation methods for them, pharmaceutical compositions containing them and their uses are provided. Compounds of general formula (VII), which are intermediates in the synthesis of the compounds of general formula (I), wherein Ar, R2, R3, m, n, T, and the carbon atom with * are defined as in the specification, are also provided.