MARTIN MONTANES, CARLOS,GICQUEL, BRIGITTE,PEREZ HERRAN, ESTHER,GONZALO ASENSIO, JESUS,ARBUES ARRIBAS, AINHOA
申请号：
CA2647287
公开号：
CA2647287C
申请日:
2007.03.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention relates to an isolated microorganism belonging to the genus Mycobacterium, characterized in that it comprises inactivating the gene Rv0757 that confers a PhoP- phenotype and inactivating a second gene that prevents the production of DIM (DIM-phenotype). Additionally, the present invention comprises the use of said microorganism for producing a vaccine for immunizing against or preventing tuberculosis.
