The present invention discloses a system for handling a surgical instrument, useful for observation and/or intervention with respect to a patients body. The system comprising a fixed support hinge which enable changing of the inclination of the system actuators system that produce the rotation movement utilized by handling surgical instrument mechanism a flexible power transmission system gear housing adapted to change the direction of the motors rotation transmitted by the flexible power transmission system and, handling surgical instrument mechanism, said mechanism comprising: a first small size moveable element, connected to the gear housing is adapted to simultaneous maneuver of a second moveable element to the four main directions, and/or any other maneuver, e.g., right and left, forward and backward and, a second moveable element that which is adapted to move the surgical instrument to another directions, zoom in and zoom out, simultaneously rotate the surgical instrument, either clockwise or counter-clockwise, simultaneously rotate the camera housing in respect to the surgical instrument clockwise and counter-clockwise.