經取代之吡啶基－環烷基－羧酸、包含其之組合物及其用途农业专利-农业学术服务平台

发明人:: 布瑞尔　尼可,布瑞爾　尼可,NAGEL, JENS,奈吉尔　杰恩,奈吉爾　傑恩,IRLBACHER, HORST,艾巴却尔　华斯特,艾巴卻爾　華斯特,ROTGERI, ANDREA,罗梯结　安德鲁,羅梯結　安德魯,SCHWEDE, WOLFGANG,先威德　沃夫根,戴罗夫　汉瑞克,戴羅夫　漢瑞克,KOPPITZ, MARCUS,科皮兹　马克斯,科皮茲　馬克斯,PETERS, MIC,布瑞尔尼可,布瑞爾尼可,奈吉尔杰恩,奈吉爾傑恩,艾巴却尔华斯特,艾巴卻爾華斯特,罗梯结安德鲁,羅梯結安德魯,先威德沃夫根,戴罗夫汉瑞克,戴羅夫漢瑞克,科皮兹马克斯,科皮茲馬克斯

摘要：: The present invention relates to substituted Pyridyl-cycloalkyl-carboxylic acids of general formula (I) as described and defined herein, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular in mammals, such as but not limited to diseases associated with pains, or for the treatment or prophylaxis of pain syndromes (acute and chronic), inflammatory-induced pain, pelvic pain, cancer-associated pain, endometriosis-associated pain as well as endometriosis and adenomyosis as such, cancer as such, and proliferative diseases as such like endometriosis.本發明係關於如本文所述及定義之通式(I)之經取代之吡啶基-環烷基-羧酸、製備該等化合物之方法、包含該等化合物之醫藥組合物及組合，以及該等化合物之用途，其用於製造用來治療或預防特別是哺乳動物之疾病(例如(但不限於)與疼痛相關之疾病)或用來治療或預防疼痛症候群(急性及慢性)、發炎引起之疼痛、骨盆疼痛、癌症相關疼痛、子宮內膜異位症相關之疼痛以及子宮內膜異位症及子宮肌腺症本身、癌症本身及增生性疾病本身(如子宮內膜異位症)的醫藥組合物。