The present invention provides compositions for use in recovering and/or ameliorating deterioration of physiological functions due to aging. Provided are: a cell overexpressing GDF6 protein or an miR-17 family member； a composition for use in treating a senescence-related condition, containing GDF6 protein； a composition for use in treating a senescence-related condition, containing a human expression vector for GDF6 protein or an miR-17 family member； and a composition for use in treating a senescence-related condition, containing a cell secreting GDF6 protein.
