FARFEL, Gail,LOCK, Michael,GALER, Bradley S.,MORRISON, Glenn,BOYD, Brooks M.
申请号：
AU2018342072
公开号：
AU2018342072A1
申请日:
2018.09.25
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
A method of reducing convulsive seizure frequency in a human patient diagnosed with Dravet syndrome, comprising administering to the patient a therapeutically effective dose of fenfluramine or a pharmaceutically acceptable salt, base, acid or amine thereof, and repeating the administering over a period of days until the patient exhibits a significant reduction (e.g., 40% or greater) from baseline in convulsive seizure frequency. In some embodiments of the method, convulsive seizures are completely eliminated for 10 days or more, 20 days or more, 30 days or more, 50 days or more, 100 days or more.
