WEIGHT, ALISHA K.,LARSON, ALYSSA M.,LANGER, ROBERT S.,KLIBANOV, ALEXANDER M.,LOVE, KEVIN,CRANE, ALAN
申请号:
CA2924069
公开号:
CA2924069A1
申请日:
2014.09.11
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous or intramuscular injection, rather than by lengthy intra-venous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and viscosity-reducing ionic liquids.