LARSON, ALYSSA M.,LOVE, KEVIN,WEIGHT, ALISHA K.,CRANE, ALAN,LANGER, ROBERT S.,KLIBANOV, ALEXANDER M.
申请号:
CA2923843
公开号:
CA2923843A1
申请日:
2014.09.11
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous or intramuscular injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and viscosity-lowering water soluble organic dyes.