INSTITUTE OF PHYSIOLOGY OF AS CR;INSTITUTE OF PHYSIOLOGY OF AS CR, V.V.I.; V.V.I.;RCD, S.R.O.
发明人:
JEZEK, PETR,NEKVASIL, MILOS,POUCKOVA, PAVLA
申请号:
CA2665762
公开号:
CA2665762C
申请日:
2007.11.27
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Liposomal gel hydrophobic phthalocyanine (FCH) preparation for photodynamic therapy of tumors and other diseases is composed of lecithin liposomes or liposomes on the basis of other lipids, with incorporated curing drug, which can be chosen either from a group including hydrophobic hydroxyaluminum phthalocyanine, hydrophobic aluminum phthalocyanine, hydrophobic zinc phthalocyanine, hydrophobic silicone phthalocyanine, or organic silicone phthalocyanine, or hydrophobic phthalocyanine without the core metal; while resulting liposomes are mixed in ratios of 10:1 to 1:10 with a translucent gel, advantageously on the basis of carboxymethylcellulose. The added curing drug can be coated by glucose or other saccharides, by polyethylenglycol or other usable polymers, as lecithin or other lipids, or by sodium chloride or other salts usable in pharmacology..