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Method of making a high enhancer-loading polyacrylate formulation for transdermal applications
专利权人:
发明人:
Jay Audett,Jianye Wen,Eli J. Goldman,Robert M. Gale,Allison Luciano,Paul B. Foreman,Eric N. Silverberg
申请号:
US13776452
公开号:
US08758808B2
申请日:
2013.02.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
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