Clamp assemblies are used in medical device and system, so that executing the dissection single jaw assembly of multiple modes. Clamp assemblies may include various features so that this versatility. For example, clamping jaw is designed to that there is specific curvature to help to execute that specific anatomical step. In addition, clamping jaw can have different thickness and widths across one section of one or more pawl with specific anatomical step but also being readily achieved. Further, ridge can be formed in two interior peripheries equipped with jaw, to provide additional dissection ability. In some embodiments, jaw component may include more than two clamping jaw, is variation in the timing of clamping jaw and rate, disposes at least two clamping jaws. Other system, device and method is also provided.