Jaw assemblies for use in medical devices and systems to enable the performance of multiple modes of dissection using a single jaw assembly are provided. The jaw assembly can include a variety of features to enable this versatility. For example, the jaws can be designed to have particular curvatures that are conducive to performing particular dissection steps. Further, the jaws can have different thicknesses and widths across a length of one or more jaws to also enable particular dissection steps to be more easily performed. Still further, ridges can be formed on both inner and outer surfaces of the jaws to provide additional dissection capabilities. In some embodiments, the jaw assemblies include more than two jaws, with the timing and rate of the jaws deployment being varied for at least two of the jaws. Additional systems, devices, and methods are also provided.