This invention pertains generally to antibacterial compounds of Formula I, as further described herein, and pharmaceutically acceptable salts and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds to treat infections such as those caused by Gram-negative bacteria.本發明概言之係關於式I之抗細菌性化合物,如本文進一步闡述,及其醫藥上可接受之鹽及調配物。在某些態樣中,本發明係關於使用該等化合物治療諸如由革蘭氏陰性細菌(Gram-negative bacteria)引起之彼等感染之方法。