Through the present invention, a drug dispensing machine 10 is realized having a wide range of selection when supplying powdered medicine. When a plurality of powdered medicine supply devices are provided upstream from a packaging device 20, a rotary-distribution-type first powdered medicine supply device 30 and a weighing-apportionment-type second powdered medicine supply device 40 are provided in a row arrangement, and a charging hopper guide mechanism 51 is provided for directing powdered medicine from the second powdered medicine supply device 40 to a charging hopper 22 of the packaging device 20. A powdered medicine feeder guide mechanism 52 for directing powdered medicine from the second powdered medicine supply device 40 to a powdered medicine feeder 31 of the first powdered medicine supply device 30, an annular receiving member guide mechanism for directing powdered medicine from the second powdered medicine supply device 40 to a rotary annular receiving member 32 of the first powdered medicine supply device 30, and an alternative choosing means for causing only one of either of the guide mechanisms to function are also provided.