Device (1) for the extraction of blood or a blood compound, that comprises a tube (10), a piston assembly (50), a handle assembly (30) that can be clipped to the piston assembly (50), and a perforable sealing element (70) that prevents the flow of fluid from a sealed interior space (15a) of the tube (10) towards a longitudinal interior cavity (35) of the handle assembly (30) located adjacent to a separable area (33) of the handle assembly (30). In use, the handle assembly (30) is pushed to the bottom of the tube (10), causing the handle assembly (30) to be clipped to the piston assembly (50); the handle assembly (30) and piston assembly (50) are then moved rearwards forming a vacuum in the space (15a); the piston assembly (50) is clipped to an end cap (90) of the tube (10) and the gripping portion (32) of the handle assembly (30) is separated, obtaining a vacuum container with a perforable closure.一種用於抽取血液或血液複合物的裝置(1)包含一管(10)、一活塞總成(50)、一可扣夾於該活塞總成(50)的把手總成(30)、及一可穿孔的密封件(70),該可穿孔的密封件防止從該管(10)的一密封內空間(15a)朝向該把手總成(30)的一縱向內腔室(35)的流體流動,該縱向內腔室位置在相鄰於該把手總成(30)的一可分離區(33)。在使用時,將該把手總成(30)推到該管(10)的底部,導致該把手總成(30)扣夾於該活塞總成(50);然後該把手總成(30)和活塞總成(50)向後移動,以在該空間(15a)中形成真空;該活塞總成(50)扣夾於該管(10)的一端蓋帽(90),且使該把手總成(30)的握持部(32)分離,得到一具有一可穿孔閉合的真空容器。