Gabriel M. Gutierrez,James Pannucci,Amy Noe,Steve Chienwen Huang,Scott Winram
申请号:
US14097799
公开号:
US20150158941A1
申请日:
2013.12.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This disclosure provides antibodies that are useful for preventing and/or treating malaria. The epitope to which the antibodies bind is in close proximity to the conserved proteolytic cleavage site of P. falciparum circumsporozoite protein (CSP), and the antibodies provided in this disclosure can prevent cleavage and inhibit P. falciparum sporozoites from invading the liver.