Leidos, Inc.;The United States of America, as represented by the Secretary, Dept. of Health and Human Services
发明人:
Gabriel M. Gutierrez,James Pannucci,Amy Noe,Steve Chienwen Huang,Scott Winram,Annie Xiaoyan Mo
申请号：
US15056458
公开号：
US10160802B2
申请日:
2016.02.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This disclosure provides antibodies that are useful for preventing and/or treating malaria. The epitope to which the antibodies bind is in close proximity to the conserved proteolytic cleavage site of P. falciparum circumsporozoite protein (CSP), and the antibodies provided in this disclosure can prevent cleavage and inhibit P. falciparum sporozoites from invading the liver.
