Refers to FUSED Heterocyclic compounds of formula (i) where R1 is alkyl, optionally substituted by Halogen C1 - 6 R2 is a Hydrocarbon group or a Heterocyclic Group, heterociclil not Aromatic carbonyl Group optionally substituted X is s, and a is CH or their Salts.Preferred compounds are: 2 - (2-chlorophenyl) - 6 - (2 - methyl - 1h-pyrazol-4-yl) thieno [3,2-d] pyrimidine 4 (3H) - One, 2 - {[(3S) - 3 - fluoropirrolidin - triazin-1-yl] methyl) - 6 - (5 - methyl - 1h-pyrazol-4-yl) thieno [3,2-d] pyrimidine 4 (3H) - One, among others. These compounds have Inhibitory activity of the Cell Division Cycle 7 (Cdc7) is useful for the Prevention or treatment of cancerSE REFIERE A COMPUESTOS HETEROCICLICOS FUSIONADOS DE FORMULA (I) DONDE: R1 ES ALQUILO C1-6 OPCIONALMENTE SUSTITUIDO CON HALOGENO R2 ES UN GRUPO HIDROCARBONADO, GRUPO HETEROCICLICO O GRUPO HETEROCICLIL-CARBONILO NO AROMATICO OPCIONALMENTE SUSTITUIDOS X ES S Y ES CH O UNA DE SUS SALES. SON COMPUESTOS PREFERIDOS: 2-(2-CLOROFENIL)-6-(5-METIL-1H-PIRAZOL-4-IL)TIENO[3,2-d]PIRIMIDIN-4(3H)-ONA, 2-{[(3S)-3-FLUOROPIRROLIDIN-1-IL]METIL}-6-(5-METIL-1H-PIRAZOL-4-IL)TIENO[3,2-d]PIRIMIDIN-4(3H)-ONA, ENTRE OTROS. DICHOS COMPUESTOS TIENEN UNA ACTIVIDAD INHIBIDORA DEL CICLO DE DIVISION CELULAR 7 (Cdc7) SIENDO UTIL PARA LA PREVENCION O EL TRATAMIENTO DE CANCER
