An image pickup apparatus includes: a solid-state image pickup device in which one surface of a substrate is partitioned into a light-receiving portion region in which a light-receiving portion is provided that generates an image pickup signal of a picked-up optical image of a subject, a circuit portion region in which a circuit portion is provided that performs signal processing of the image pickup signal generated by the light-receiving portion and generates a driving signal that drives the light-receiving portion, and a terminal portion region in which a plurality of terminals are provided that are used when inputting and outputting signals between the circuit portion and an external apparatus； and an objective optical portion having an objective lens unit including a unit main body equipped with an objective lens group for forming an optical image of the subject and a holding barrel in which the unit main body is fixedly installed, and a prism that bends an optical axis of the unit main body and guides the optical image that passes through the objective lens unit to the light-receiving portion of the solid-state image pickup device. The prism of the objective optical portion is disposed on the light-receiving portion region of the substrate, and the holding barrel included in the objective lens unit of the objective optical portion is disposed on the circuit portion region.
