DEAN NICHOLAS M,KROCHMAL LINCOLN,HARDEE GREGORY,FOULKES J GORDON,ODONNELL NIALL,YOUNG LEROY,JEWELL MARK
申请号：
IN7707/DELNP/2013
公开号：
IN2013DN07707A
申请日:
2013.09.02
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
This invention provides methods of preventing formation of or treating fibrotic lesions including skin scars such as keloids and hypertrophic scars which comprise administering to the subject by one or more injection a compound which comprises a modified oligonucleotide such as a modified antisense oligonucleotide siRNA or oligodeoxyribonucleotide which inhibits expression of protein involved in fibrosis. Dosing of the antisense using an intradermal threading technique is also described.
