Disclosed is a method for initializing an analyte measurement system (1, 2, 3), the analyte measurement system (1, 2, 3) being designed for continuous in-vivo measurement of a body fluid analyte concentration. The method including the steps of:a) providing the analyte measurement system (1 , 2, 3,) with a control device (3) and a separate skin-mountable patch device (1, 2), the patch device (1, 2) including a disposable unit (1) and an electronics unit (2), the disposable unit (1) including a transcutaneous analyte sensor (10) and machine-readable sensor identifier (121), the disposable unit (1) being configured to releasable couple for an application time period to the disposable unit (1)；b) providing a number of stored initialization data sets in a remote database system (4), each stored initialization data set comprising initialization data for an analyte sensor batch；c) reading, via a reading device (31) of the control device (3), the sensor identifier from the disposable unit (1) into the control device (3) and transmitting the sensor identifier to the remote database system；d) determining a matching initialization data set, the matching initialization data set being a stored initialization data set that matches the sensor identifier；e) transmitting the matching initialization data set from the remote database system to the control device (3)；f) transmitting the matching initialization data set to the electronics unit (2) and storing the matching initialization data set in a memory (21) of the electronics unit (2).
