Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same
Susan Zeun;Angelo Secci;Jan Nedrikat;Holger Zimmermann;Pol Boudes
发明人:
Susan Zeun,Pol Boudes,Angelo Secci,Jan Nedrikat,Holger Zimmermann
申请号:
US11609705
公开号:
US08153616B2
申请日:
2006.12.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The multiphase combination preparation for oral therapy of dysfunctional uterine bleeding and for oral contraception contains a first phase consisting of 2 daily dosage units, each containing 3 mg of estradiol valerate or <;3 mg of estradiol; a second phase consisting of a first group of 5 daily dosage units, each consisting of a combination of 2 mg of dienogest with 2 mg of estradiol valerate or <;2 mg of estradiol, and a second group consisting of 17 daily dosage units, each consisting of a combination of 3 mg of dienogest with 2 mg of estradiol valerate or <;2 mg of estradiol; a third phase consisting of 2 daily dosage units, each containing 1 mg of estradiol valerate or <;1 mg of estradiol; and another phase consisting of 2 daily dosage units of a pharmaceutically harmless placebos.