A vitrectomy probe for treating an eye of a patient, the probe including a body arranged for grasping by a surgeon, and a photodisruption element extending from the body. The photodisruption element includes a needle having a main lumen extending from the body, the needle comprising a port at an end, a fiber cannula within the main lumen, the fiber cannula having a fiber lumen, and an optical fiber within the fiber lumen, the optical fiber being mechanically agitatable within the fiber lumen.