SEL D'UN INHIBITEUR D'EGFR, FORME CRISTALLINE CORRESPONDANTE ET UTILISATIONS CORRESPONDANTES

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专利权人:

SUNSHINE LAKE PHARMA CO.; LTD.

发明人:

LIU, BING,ZHANG, WEIHONG,ZHANG, YINGJUN

申请号：

CA3001655

公开号：

CA3001655A1

申请日:

2016.10.18

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The invention relates to a salt, a hydrate or a crystalline form of an EGFR inhibitor, and use thereof. Specifically it relates to 4-[ (3-chloro-4-fluorophenyl) amino] -7-methoxy-6- [3-[ (1R, 6S) -2, 5-dioxa-8-azabicyclo [4.3.0] nonan-8-yl] propoxy] quinazoline dimethanesulfonate, hydrate and a crystalline form thereof； the invention also relates to a preparation method of the crystalline form disclosed herein, a pharmaceutical composition containing the crystalline form, and uses thereof for treating proliferative disorders.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/