ZENG, QINGPING,TORO, ANDRAS,PATTERSON, JOHN BRUCE,WADE, WARREN STANFIELD,ZUBOVICS, ZOLTAN,YANG, YUN,WU, ZHIPENG
申请号：
CA2795350
公开号：
CA2795350C
申请日:
2011.04.05
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Compounds which directly inhibit IRE-1 ot activity in vitro, prodrugs, andpharmaceutically acceptable salts thereof Such compounds and prodrugs areusefulfor treating diseases associated with the unfolded protein response or withregulatedIRE1-dependent decay (RIDD) and can be used as single agents or in combinationtherapies. Compounds of the present invention include those of formula (A-I):(see formula A-I)
