The present invention relates to nalmefene for use in the reduction of alcohol consumption in a patient with alcohol dependence who has a high drinking risk level. The present invention also relates to nalmefene for use in the reduction of alcohol consumption in a patient with alcohol dependence who maintains a high DRL after an observation period following initial assessment.USO DE NALMEFENO PARA PREPARAR UN MEDICAMENTO ÚTIL PARA LA REDUCCIÓN DEL CONSUMO DE ALCOHOL EN UN PACIENTE CON DEPENDENCIA DEL ALCOHOL.