INTERNALIZING HUMAN MONOCLONAL ANTIBODIES TARGETING PROSTATE AND OTHER CANCER CELLS

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专利权人:

The Regents of the University of California

发明人:

Bin Liu

申请号：

US16517401

公开号：

US20200040094A1

申请日:

2019.07.19

申请国别(地区):

US

年份:

2020

代理人:

摘要：

In various embodiments various cancer specific antibodies and immunoconjugates are provided. In certain embodiments the antibodies specifically bind and are internalized into a prostate cancer cell, where the antibodies specifically binds cells that express or overexpress a CD46, and where the antibodies specifically bind sushi domain 1 of said CD46 (CD46 CPP1).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/