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INTERNALIZING HUMAN MONOCLONAL ANTIBODIES TARGETING PROSTATE AND OTHER CANCER CELLS
专利权人:
The Regents of the University of California
发明人:
BIN LIU
申请号:
US15390378
公开号:
US20170240643A1
申请日:
2016.12.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
In various embodiments various cancer specific antibodies and immunoconjugates are provided. In certain embodiments the antibodies specifically bind and are internalized into a prostate cancer cell, where the antibodies specifically binds cells that express or overexpress a CD46, and where the antibodies specifically bind sushi domain 1 of said CD46 (CD46 CPP1).
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