Fractional laser surgical equipment having multiple purposes including treatment of the vagina includes a laser controller in which a laser supply portion is formed at one end of a main body having a space therein and a laser emission hole is formed at the other end of the main body, and a laser irradiation portion formed to enable attachment to or detachment from the laser controller and having a pair of guide portions formed at a part making contact with the affected part such that the laser is irradiated between the guide portions. The fractional laser surgical equipment enables accurate laser targeting of the affected part, can prevent various side effects such as repetitive laser irradiation, can wash in advance and antibacterially treat insertion portions so as to be more sanitary since the insertion portions are attachable and detachable, and can reduce the time for operation preparation.