Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
发明人:
Altevogt, Peter,Luttgau, Sandra,Moldenhauer, Gerhard,Hazin, John
申请号：
AU2015327064
公开号：
AU2015327064A1
申请日:
2015.09.28
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present disclosure relates to a binding molecule binding to L1, which is capable of binding to the same L1 epitope recognized by the monoclonal antibody L1-OV52.24, and/or which competes with the monoclonal antibody L1-OV52.24 for binding to L1, wherein the variable part of the light chain of L1-OV52.24 comprises the sequence according to SEQ ID No: 1 or wherein the light chain is encoded by SEQ ID No: 3, and wherein the variable part of the heavy chain of L1-OV52.24 comprises the sequence according to SEQ ID No: 2 or wherein the heavy chain is encoded by SEQ ID No: 4, nucleic acids encoding the binding molecules, uses thereof and pharmaceutical compositions comprising the binding molecules.
