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Compounds useful for treating aids
专利权人:
INSTITUT CURIE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE MONTPELLIER 2;SOCIETE SPLICOS
发明人:
Jamal Tazi,Florence Mahuteau,Romain Najman,Didier Scherrer,Noelie Campos,Aude Garcel
申请号:
US14256334
公开号:
US09908869B2
申请日:
2014.04.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A compound having the following formula or a pharmaceutically acceptable salt thereof:where:R″ is a hydrogen atom or a (C1-C4)alkyl group;n′ is 1 or 2;n is 1, 2, or 3;R independently represents a hydrogen atom, a halogen atom, or a group selected from a (C1-C3)alkyl group, a —CN group, a hydroxyl group, a —NR1R2 group, a —COOR1 group, a (C1-C3)fluoroalkyl group, a —NO2 group, a (C1-C3)fluoroalkoxy, and a (C1-C4)alkoxy group;R′ is a hydrogen atom, a halogen atom, or a group selected from a (C1-C3)alkyl group, a —COOR1 group, a —NO2 group, a —NR1R2 group, a (C1-C4)alkoxy group, and a CN group;R1 and R2 are a hydrogen atom or a (C1-C3)alkyl group;with the proviso that when R and R′ are not simultaneously a hydrogen atom:when n is 1, R is not a methyl group in an ortho or para position with respect to N,when R′ is a hydrogen atom, R is not a bromine atom or a chlorine atom, andwhen R is a hydrogen atom, R′ is not a methyl or ethyl group, a —COOH group, a —COOC2H5 group, or a bromine atom that is in an ortho position of the bond linked to NR″.
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