Percutaneous absorption enhancer and high safety, excellent percutaneous absorption promoting effect, the usability, the present invention relates to a transdermal preparation as well made by blending said percutaneous absorption accelerator. By incorporating the external preparation for skin patch preparation such as a percutaneous absorption enhancer of the present invention with the additive (ii) specific be increased significantly the skin permeability of the drug (i) and lactic acid, possible.本発明は、経皮吸収促進効果に優れ、かつ安全性、使用性の高い経皮吸収促進剤、並びに該経皮吸収促進剤を配合してなる経皮吸収型製剤に関する。(i)乳酸、及び(ii)特定の添加剤からなる本発明の経皮吸収促進剤を、貼付製剤等の皮膚外用剤に配合することにより、薬物の皮膚透過性を顕著に増大させることができる。
