MICROPARTICULES ENROBEES DE MINERAUX PERMETTANT LA CO-ADMINISTRATION DE MOLECULES ANTI-INFLAMMATOIRES ET D'ACIDES NUCLEIQUES EN VUE D'AMELIORER LES RESULTATS DE L'ADMINISTRATION DE GENES
MURPHY, WILLIAM L.,KHALIL, ANDREW SALIM,YU, XIAOHUA
申请号：
CA3068917
公开号：
CA3068917A1
申请日:
2018.07.05
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonucleic acid, and an interferon binding protein. Ribonucleic acids and interferon binding proteins can be adsorbed to the mineral layer, can be incorporated into the mineral layer, and combinations thereof. Also disclosed are methods for co-delivery of ribonucleic acids and interferon binding proteins and methods for treating inflammatory diseases using mineral coated microparticles having a mineral layer to provide co-delivery of ribonucleic acids and interferon binding proteins.
