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FUNCTIONALIZED NANOPARTICLES AND METHODS OF MAKING AND USING SAME
专利权人:
Cornell University
发明人:
Kai MA,Ulrich B. WIESNER
申请号:
US16614975
公开号:
US20200179538A1
申请日:
2018.05.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Described is a versatile surface modification approach to, for example, modularly and orthogonally functionalize nanoparticles (NPs) such as, for example, PEGylated nanoparticles, ith various types of different functional ligands (functional groups) on the NP surface. It enables the synthesis of, for example, penta-functional PEGylated nanoparticles integrating a variety of properties into a single NP, e.g., fluorescence detection, specific cell targeting, radioisotope chelating/labeling, ratiometric pH sensing, and drug delivery, while the overall NP size remains, for example, below 10 nm.
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