An endoscope treatment tool includes: a tubular sheath member insertable into a channel of an endoscope; a wire inserted into the interior of the member in such a manner that the wire can be advanced/retracted in the longitudinal direction of the member; and a distal-end treating portion provided at the distal end of the wire and made to protrude from/be pulled into a distal-end opening in the member by advancing/retracting the wire, wherein the member is configured having a two-layer structure in which a metal coil and a resin tube are layered in the radial direction and secured to each other, in the coil, lateral cross-sectional shapes of portions of a strand that are adjacent to each other in the longitudinal direction have complementary depression and protrusion that are brought into tight contact with each other, and the tube has a flexural rigidity greater than that of the coil.