The present invention relates to a medicament for oral administration containing at least one estrogen and/or one gestagen and at least one probiotic bacterial strain, such as for example lactobacillus species.The medicament according to the invention is used either for oral contraception or for hormone therapy (HT), during which it can simultaneously serve for the stabilization of the vaginal environment and hence the prevention of infectious diseases, such as for example vaginal mycosis, bacterial vaginosis and/or bladder inflammation (bacterial cystitis) or the prevention of urogenital symptoms, e.g. dyspareunia and dysuria.The present invention further relates to pharmaceutical combination preparations which contain dosage units containing an aforesaid medicament and further dosage units containing exclusively a probiotic bacterial strain.
